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In 1860, Albert Niemann, a chemistry graduate student at Göttingen University, published his doctoral dissertation, which described the isolation of cocaine from coca leaves and the numbness it caused when applied to his tongue. By 1880, reports of cocaine’s miraculous properties abounded. It was purported to cure morphine and alcohol addiction, tuberculosis, and even impotency. The young Viennese physician Sigmund Freud used cocaine in an attempt to cure a friend of morphine addiction; he succeeded in transferring the friend’s addiction to cocaine. In 1884, Freud’s colleague, the Austria..

Our series of posts about the scientific research of Salvia divinorum is now six months old, and we’ve looked at a whole spectrum of research into this unique hallucinogen: from human studies of the subjective psychedelic effects of the drug, to the nuts and bolts of how Salvia’s pharmacology effects our brain, and even how Salvia’s main psychedelic component could be an important tool in the treatment of pain or addiction. Since these topics are wide ranging and often confusing, we thought now would be a good time to summarise everything we’ve covered so far and bring them together, to g..

As I mentioned in my last post about Salvia divinorum Research, I was going to take a look at some papers on Salvia divinorum and summarise them here. Well, here we go! The following post is a summary of a paper published last year in the journal Psychopharmacology entitled "Acute and post-acute behavioral and psychological effects of salvinorin A in humans", by Peter H Addy. Introduction The paper begins with a bit of background on Salvinorin-A, the active compound in Salvia divinorum. Unlike "classic" hallucinogens such as psilocin, LSD, etc, salvinorin-A does not bind to the 5-HT2A..

Our tropical herbal incense blend Pineapple Express Mrk II is available in 1g or 3g packs Smooth, satisfying, and very tropical; Pineapple Express Mrk II is new and improved version of the old Pineapple Express and was formulated with the summertime on our minds. Take it easy with just a sprinkle of our fruity herbal mix and you’ll be whisked away to a tranquil paradise. Pineapple Express is one of our more potent herbal incense, so we recommend it for those who enjoy a stronger aroma, or simply for anyone who is a fan of the exotic Ananas comosus (better known as the Pineapple). ..

The power of psilocybin (a main component in magic mushrooms) as medicine is being slowly realised by medical and research professionals around the world. It has been long understood that affecting the conscious state through psychedelics can have a profound effect on those who are suffering from illnesses or coming to the end of their lives, but researchers are suggesting that magic mushrooms possess a broader multitude of medicinal qualities. Dr. David A. Nichols PHD, a co-founder at the Heffer Research Institute, yesterday published his research, the conclusion of multiple studies, that ..

We’ve heard plenty of glowing reports on our flagship herbal incense ‘Green Dream’ but we’re heeding the call from others, eager to get on the herbal incense highway, but perhaps not in the fast-lane. Green Dream Light is still akin to a sports car, but it’s more of a classic, the ride is smoother and less aggressive, 0-60 in just about the right number of seconds. Ingredients: Mullein 1-(5-fluoropentyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester ..

Available from Legalhighlabs 8 Ball is legendary on the research chemical powder circuit, even its name sparks fear into the hearts of our puny competition. If you consider 8 Ball as a legal highs Godzilla, then the laughable imitations are the humans scattered below like ants fleeing from our ferocity. One of our flagship powders, 8 Ball is a high quality research reagent, with proven long lasting effects just minutes after use. Ingredients: N-methyl-2,3-dihydro-1H-inden-2-amine Ethyl 4-aminobenzoate 1,3,7-Trimethylpurine-2,6-dione May contain lactose ..

There is quite a lot of controversy across Europe over legal highs at the moment which I wish only to deal with the facts to allow you to make your own decision and opinion on them. I want to give you as much information about legal highs as I can which I have sourced from reputable drug information services and websites such as Talk To Frank. I hope the information I provide gives you the knowledge on whether or not you want to take them, as from my experience if you’re going to take something you are going to take it regardless of what anyone says to you and only you can make the decision. W..

Although marijuana (cannabis) has been used in medicine for thousands of years, its place as a drug in modern medicine has been the subject of intense debate. Among the earliest Western medical reports was one written in 1839 by William O’Shaughnessy, an Irish physician working in India. He noted that cannabis was nontoxic in animals and that it suppressed convulsions and relieved muscle spasms and pain in his patients. In 1912, the author of a leading textbook of therapeutics spoke with praise about cannabis’s value in relieving cough, pain, menstrual cramps, and the tremors of Parkinson’s di..

Identification: Climbing vine or shrub with adventitious roots, rapidly spreading. Trumpet- shaped flower, white or blue, but many species have various hues. Flower typically opens in morning. Seed is black and contains the drug. Habitat: Over 500 species worldwide—tolerant of both poor, dry soils and wetlands. Mexican varieties are especially hallucinogenic. I. purpurea (“manto de la Virgen”) found in the Yucatán has been used for hundreds of years in Mayan medicine and rituals. Seeds also used by the indigenous Zapotecs from which they made the powerful drug badoh negro; morning glories o..

Identification: Evergreen shrub grows 7'–10' tall, with straight branches. Thin leaves are oval and taper at both ends. Small flowers in clusters with short stalks; corolla is composed of 5 yellowish-white petals with heart-shaped anthers. Pistil has 3 carpels; berries red. Habitat: Andean mountain dweller (Peru, Bolivia). Toxins/Drugs: Coca alkaloid. When chewed, coca acts as a mild stimulant and suppresses hunger, thirst, pain, and fatigue. Historical documentation suggests that raw coca is not addictive. There appear to be no deleterious effects from the consumption of the leaf in its na..

Identification: Small to large plant. Potent hybrids are smaller. Leaves are 5-bladed, serrated (toothed) leaflets. Plant has a tough fibrous stem. Green female flower buds are the sought after part. Habitat: Subtropical and High-potency hybrid marijuana buds temperate; wild strain is drought tolerant and will grow equally well on drained and marshy wet soils. In Michigan, before the legalization of medical marijuana in 2008, it was typically grown in canvas or coarse fiber grain sacks or flour bags stuffed with compost, and then placed atop rich wetland earth (or any other somewhat inacces..

Other Names: Ambihuasca, ambiwáska, ayawáska, biaxii, caji, caapi, calawaya, cipó, daime, daba, dapá, djungle tea, djunglehuasca, doctor, dschungel ambro- sia, el remdio, hoasca, honi, kaapi, kahi, hakpi, la purga, meti, mihi, natema, natemä, nepe, nepi, nixi honi, nixi paé, notema, ohoasca, pilde, pildé, pinde, pindé, remedio, sachahuasca, snato daime, tea, the brew, vegetal, yagé, yajé, yaxé Identification: A shrub or climbing, twisting vine (or liana) with chocolate brown, smooth bark. Leaves are opposite, 6"–7" long, 3" wide, oval, double tapered, margins entire. Flowers are pink with 1..

Substance type: tryptamine (indole alkaloid) Empirical formula: C12H16N2 Other Names: Dimethyltryptamin, dimethyltryptamine, 3-(2- [dimethylamino]ethyl)-indol, N,N-dimethyl-trypt- amine, N,N-DMT, nigerin, nigerina, nigerine (1946) Pure DMT has been described as an aphrodisiac and psychedelic in various cultures. It is also pres- ent in many traditional aphrodisiacs: acacia, aya- huasca, cumala, epená, cowitch, zanthoxylum, mimosa pudica, some soma plants, and toad secretions. R. H. F. Manske first created DMT as a syn- thetic substance in a laboratory in 1931. Psychi- atric experiments w..