Diclazepam is a positive allosteric modulator of the benzodiazepine receptors, paticulary the ‘diazepam sensitive’ sites. It was designed and developed by a team at Hoffmann-La Roche, led by Leo Sternbach (US Patent 3136815).


While Etizolam is a thienodiazepine research chemical compound that is a benzodiazepine analog. The etizolam molecule is different from a benzodiazepine in that the benzene ring has been substiuted by a thiophene ring. It contains amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties.